| REVIEW ARTICLE |
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| Year : 2017 | Volume
: 1
| Issue : 1 | Page : 55-61 |
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Estrogen Biosynthesis and Its Regulation in Endometriosis
Qiu-Ming Qi1, Sun-Wei Guo2, Xi-Shi Liu2
1 Department of Gynecology, Shanghai Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China
2 Department of Gynecology, Shanghai Obstetrics and Gynecology Hospital, Fudan University; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Fudan University, Shanghai 200011, China
Correspondence Address:
Xi-Shi Liu
Department of Gynecology, Shanghai Obstetrics and Gynecology Hospital, Fudan University Shanghai College of Medicine, 419 Fangxie Road, Shanghai 200011
China
 Source of Support: None, Conflict of Interest: None  | 6 |
DOI: 10.4103/2096-2924.210698
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Endometriosis is a common benign gynecological disorder with an enigmatic etiology and pathogenesis. It affects approximately 10% women of reproductive age. Although its etiology and pathogenesis remain poorly understood, it is characterized by the elevated local production of estrogen in the endometriotic tissues. In this paper, we review the mechanisms of estrogen biosynthesis and its regulation in endometriosis.
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